Overexpressed lncRNA LINC00893 Suppresses Progression of Colon Cancer by Binding with miR-146b-3p to Upregulate PRSS8

<div>The inhibitory effect of LINC00893 overexpression on colon cancer cells. (a) LINC00893 expression in five different colon cancer cell lines and control cells was analyzed by PCR. (b) MTT assay was performed to evaluate cell viability in HCT116 and SW620 cells under the condition of LINC00893 overexpression. (c) A wound-healing assay was used to evaluate migration capacity in colon cancer cells. (d) Transwell assay was used to reveal cell invasion of HCT116 and SW620 cells in LINC00893 OE and other groups. (e) EdU assay was performed to evaluate cell proliferation of HCT116 and SW620 cells in indicated groups. (f) The apoptosis rate of colon cancer cells after indicated treatment was measured by the TUNEL assay. 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Journal of Oncology

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Figure 2

Figure 2: Overexpressed lncRNA LINC00893 Suppresses Progression of Colon Cancer by Binding with miR-146b-3p to Upregulate PRSS8 