Selection of lncRNAs That Influence the Prognosis of Osteosarcoma Based on Copy Number Variation Data

Figure 3

Screening of prognostic lncRNAs in osteosarcoma: (a) lncRNA expression in CNV-gain and CNV-loss groups; (b) forest map based on the univariate Cox regression analysis of lncRNAs; (c) fivefold cross-validation for tuning parameter selection in the LASSO model. Partial likelihood deviance is plotted against log (), where is the tuning parameter. Dotted vertical lines were drawn at the optimal values by minimum criteria and 1-s.e. criteria (left). LASSO coefficient profiles of the 3 lncRNAs associated with the prognosis of osteosarcoma in the univariate Cox regression analysis (right).

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