Circular RNA KIF4A Promotes Liver Metastasis of Breast Cancer by Reprogramming Glucose Metabolism

Figure 5

Cancer metastasis and tumor proliferation are promoted by CircKIF4A in vitro and in vivo. (a) Visible tumor nodules of liver metastasis. (b) Representative images of liver metastatic nodules. (c) Hematoxylin-eosin-stained sections of liver metastatic nodules (scale bar = 50 μm). (d) Transfections with circKIF4A mimics increased glucose uptake and lactate production, which was reversed by the supplement of miR-335.

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