Periplocin Induces Apoptosis of Pancreatic Cancer Cells through Autophagy via the AMPK/mTOR Pathway

Figure 7

Periplocin increases autophagy and apoptosis in pancreatic cancer tumors in vivo. (a) TUNEL staining of CFPAC1 tumor sections following various treatments, scale bar = 100 μm. (b) Immunohistochemistry staining for LC3B in tumors in vivo, scale bar = 20 μm (400x). (c) Expression of cleaved-caspase3 and LC3BII/I in the CFPAC1 tumor model as detected by Western blotting following different treatments.

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