miR-193a-5p Enhances the Radioresistance of Pancreatic Cancer Cells by Targeting ZFP57 and Activating the Wnt Pathway

Figure 4

The BxPC3-RR cells with ZFP57 overexpression and transfected with the corresponding control were injected into subcutaneous tissues of nude mice. Then, the transplanted tumor was irradiated by 10 Gy of different types of radiation once every two days for three times consecutively. (a) The nude mice with the transplanted tumors were killed after four weeks of radiotherapy at 10 Gy, and the photos were taken at the transplanted tumors. (b) The transplanted tumor volume was measured every week after radiotherapy at 10 Gy. (c) The weight of the transplanted tumor was determined. (d) The expressions of ZFP57, Ki67, Bax, CDK4, β-catenin, and γ-H2AX were determined in the transplanted tumors by WB. and .

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