The lncRNA NEAT1 Inhibits miRNA-216b and Promotes Colorectal Cancer Progression by Indirectly Activating YY1

Table 2

Univariate and multivariate analyses of clinicopathologic factors for survival in colorectal cancer patients.

Characteristics	Univariate analysis			Multivariate analysis
	HR	95% CI	value	HR	95% CI	value
Age (≥60 vs. <60 y)	0.918	0.913∼3.175	0.101
Gender (male vs. female)	0.786	0.870∼2.792	0.597
Tumour size (≥5 vs. <5 cm)	0.866	0.365∼2.015	0.743
Tumour grade (T1+T2 vs. T3+T4)	1.599	0.548∼6.224	0.344
Histological differentiation (poor vs. well)	1.148	0.061∼2.706	0.135
Nodal metastasis (N vs. P)	0.20	0.285∼0.519	0.001	6.69	3.537∼6.512	0.029
Distant metastasis (N vs. P)	2.667	2.537∼24.339	0.005	5.560	3.299∼29.566	0.028
NEAT1 expression (H vs. L)	2.271	0.114∼0.562	0.007	1.625	0.038∼3.506	0.012

HR : hazard ratio; CI : confidence interval. represents the values with significant differences. N : negative; P : positive; H : high; L : low.