Research Article
lncRNA TINCR Regulates Proliferation and Invasion of Hepatocellular Carcinoma Cells by Regulating the miR-375/ATG7 Axis
Figure 4
lncRNA TINCR localized in the cytoplasm and interacted with miR-375. (a) Fluorescence in situ hybridization (FISH) identified the location of lncRNA-TINCR in liver cancer HepG2 cells. Blue represents the nucleus, and red is lncRNA-TINCR. (b) The potential binding region with miR-375 and lncRNA TINCR and the mutant form of lncRNA TINCR were shown. (c) Luciferase reporter gene test for determining miR-375’s ability to bind to lncRNA TINCR. (d) Knockdown lncRNA TINCR affects the expression of miR-375. (e) Effect of overexpressing the lncRNA TINCR on the expression of miR-375. Scale μm; , , and .
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