Research Article
MACC1 Correlates with Tumor Progression and Immune Cell Infiltration of Colon Adenocarcinoma and is Regulated by the lncRNA ZFAS1/miR-642a-5p Axis
Table 1
Clinical characteristics of the COAD patients (TCGA).
| | Characteristic | Low expression of MACC1 (n = 239) | High expression of MACC1 (n = 239) | value |
| | T stage, n (%) | | | 0.485 | | T1 | 8 (1.7%) | 3 (0.6%) | | | T2 | 40 (8.4%) | 43 (9%) | | | T3 | 161 (33.8%) | 162 (34%) | | | N stage, n (%) | | | 0.081 | | N0 | 154 (32.2%) | 130 (27.2%) | | | N1 | 48 (10%) | 60 (12.6%) | | | N2 | 37 (7.7%) | 49 (10.3%) | | | M stage, n (%) | | | 0.038 | | M0 | 184 (44.3%) | 165 (39.8%) | | | M1 | 25 (6%) | 41 (9.9%) | | | Pathologic stage, n (%) | | | 0.019 | | Stage I | 43 (9.2%) | 38 (8.1%) | | | Stage II | 108 (23.1%) | 79 (16.9%) | | | Stage III | 60 (12.8%) | 73 (15.6%) | | | Stage IV | 25 (5.4%) | 41 (8.8%) | | | Gender, n (%) | | | 0.410 | | Female | 118 (24.7%) | 108 (22.6%) | | | Male | 121 (25.3%) | 131 (27.4%) | | | Age, n (%) | | | 0.780 | | ≤65 | 99 (20.7%) | 95 (19.9%) | | | >65 | 140 (29.3%) | 144 (30.1%) | | | Age, median (IQR) | 69 (59, 79) | 69 (58, 76.5) | 0.479 | | CEA level, n (%) | | | 0.188 | | ≤5 | 103 (34%) | 93 (30.7%) | | | >5 | 47 (15.5%) | 60 (19.8%) | | | Perineural invasion, n (%) | | | 0.842 | | No | 60 (33.1%) | 75 (41.4%) | | | Yes | 19 (10.5%) | 27 (14.9%) | | | Lymphatic invasion, n (%) | | | 0.972 | | No | 136 (31.3%) | 130 (30%) | | | Yes | 87 (20%) | 81 (18.7%) | | | OS event, n (%) | | | 0.266 | | Alive | 193 (40.4%) | 182 (38.1%) | | | Dead | 46 (9.6%) | 57 (11.9%) | | | DSS event, n (%) | | | 0.432 | | Alive | 205 (44.4%) | 193 (41.8%) | | | Dead | 29 (6.3%) | 35 (7.6%) | |
|
|
|
