Research Article
MACC1 Correlates with Tumor Progression and Immune Cell Infiltration of Colon Adenocarcinoma and is Regulated by the lncRNA ZFAS1/miR-642a-5p Axis
Table 3
Correlation between MACC1 and biomarkers of immune cells in COAD determined by GEPIA2 database.
| Immune cell | Biomarker | R value | value |
| B cell | CD19 | −0.069 | 0.25 | CD79A | −0.096 | 0.11 | CD79B | −0.12 | 0.046 |
| CD8+T cell | CD8A | −0.18 | 0.003 | CD8B | −0.091 | 0.13 |
| CD4+T cell | CD4 | 0.094 | 0.12 |
| M1 macrophage | CD80 | 0.059 | 0.33 | CD86 | 0.067 | 0.27 | TLR2 | 0.17 | 0.0044 | IRF5 | 0.19 | 0.0013 | PTGS2 | 0.046 | 0.44 |
| M2 macrophage | CD163 | 0.053 | 0.38 | MS4A4A | 0.059 | 0.33 | CD206 | 0.14 | 0.017 | CD115 | 0.15 | 0.016 | CD301 | 0.019 | 0.75 | Dectin-1 | 0.12 | 0.04 | ARG1 | 0.065 | 0.28 |
| Neutrophil | CD11b | 0.16 | 0.0089 | CEACAM8 | 0.18 | 0.0022 | ITGAM | 0.16 | 0.0089 | MPO | 0.13 | 0.028 | CCR7 | −0.02 | 0.75 |
| Dendritic cell | HLA-DPB1 | −0.058 | 0.34 | HLA-DQB1 | −0.097 | 0.11 | HLA-DPA1 | −0.042 | 0.49 | CD1C | 0.052 | 0.39 | NRP1 | 0.19 | 0.0015 | ITGAX | 0.15 | 0.012 | CD83 | 0.19 | 0.0015 |
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These results are statistically significant. ; ; . |