MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B

Figure 3

Overexpression of miR-205-5p inhibited cell migration and invasion in GC. NC mimic and miR-205-5p mimic were transfected into AGS and SGC-7901 cells by using Lipofectamine 2000. (a) Cell migration of transfected cells detected by a scratch assay. (b) Transwell assay on the migration and invasion activities of transfected cells. (c) The protein expression of COX-2, MMP2, and MMP9 detected in transfected AGS and SGC-7901 cells by western blot. <0.01 vs. NC mimic. All experiments were performed in triplicate and repeated at least three times.

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