Deferoxamine Inhibits Acute Lymphoblastic Leukemia Progression through Repression of ROS/HIF-1α, Wnt/β-Catenin, and p38MAPK/ERK Pathways

Figure 1

DFO inhibits the cell viability of Jurkat and NALM-6 cells. (A, B) Cells were treated with DFO (0, 5, 10, 50, 100, and 150 μmol/L) for 48 h. Proliferative viability was measured by CCK-8 assays. (C, D) Intracellular iron concentration was determined by the calcein-AM assay after DFO treatment on ALL cell lines for 24 h. Data are presented as mean ± SD, n = 3. .

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