MACC1 Promotes the Progression and Is a Novel Biomarker for Predicting Immunotherapy Response in Colorectal Cancer

<div>MACC1 regulates HGF/c-MET in HCT116 cells. (a) The mRNA levels of c-MET (left) and HGF (right) in tumor tissues and the surrounding noncancerous tissues (<i>n</i> = 12). (b) The mRNA levels of MACC1, c-MET, and HGF in tumor tissues (<i>n</i> = 12). (c) The analysis of the correlation between MACC1 and c-MET. (d) c-MET expression was determined by WB after interference and overexpression of MACC1. (e) QPCR examined interference and overexpression of MACC1 and MACC1 and HGF for the induction of c-MET expression in cells. (f) Statistical plot of c-MET expression detected by WB after interference and overexpression of MACC1. 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Journal of Oncology

fig3

Figure 3

Figure 3: MACC1 Promotes the Progression and Is a Novel Biomarker for Predicting Immunotherapy Response in Colorectal Cancer 