Research Article
Comprehensive Evaluation of Serum tRF-17-WS7K092 as a Promising Biomarker for the Diagnosis of Gastric Cancer
Table 2
The diagnostic performance of tRF-17-WS7K092, CEA, CA199, and CA724 in differentiating GC patients from healthy donors.
| | SEN | SPE | ACCU | PPV | NPV |
| | tRF-17-WS7K092 | 0.77 (105/136) | 0.84 (114/136) | 0.81 (219/272) | 0.83 (105/127) | 0.79 (114/145) | | CEA | 0.60 (81/136) | 0.71 (96/136) | 0.65 (177/272) | 0.67 (81/121) | 0.64 (96/151) | | CA199 | 0.51 (69/136) | 0.80 (109/136) | 0.65 (178/272) | 0.72 (69/96) | 0.62 (109/176) | | CA724 | 0.56 (76/136) | 0.74 (101/136) | 0.65 (177/272) | 0.68 (76/111) | 0.63 (101/161) | | tRF-17-WS7K092+CEA | 0.90 (122/136) | 0.60 (81/136) | 0.75 (203/272) | 0.69 (122/177) | 0.85 (81/95) | | tRF-17-WS7K092+CA199 | 0.91 (124/136) | 0.68 (92/136) | 0.79 (216/272) | 0.74 (124/168) | 0.88 (92/104) | | tRF-17-WS7K092+CA724 | 0.90 (123/136) | 0.63 (86/136) | 0.77 (209/272) | 0.71 (123/173) | 0.87 (86/99) | | tRF-17-WS7K092+CEA+CA199 | 0.95 (129/136) | 0.49 (67/136) | 0.72 (196/272) | 0.65 (129/198) | 0.91 (67/74) | | tRF-17-WS7K092+CEA+CA724 | 0.96 (131/136) | 0.44 (60/136) | 0.70 (191/272) | 0.63 (131/207) | 0.92 (60/65) | | tRF-17-WS7K092+CEA+CA199+CA724 | 0.98 (133/136) | 0.38 (51/136) | 0.68 (184/272) | 0.61 (133/218) | 0.94 (51/54) |
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SEN: sensitivity; SPE: specificity; ACCU: overall accuracy; PPV: positive predictive value; NPV: negative predictive value.
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