Research Article
Effects of Different Organ Metastases on the Prognosis of Stage IV Urothelial Carcinoma of the Bladder
Table 1
Baseline factors associated with the presence of distant metastases at diagnosis of UBUC (n, %).
| Variable | Distant metastasis (n = 1035) | Without distant metastasis (n = 2068) |
| Age, y | | | <40 | 7 (0.7) | 14 (0.7) | <60 | 215 (20.8) | 495 (23.9) | <80 | 587 (56.7) | 1206 (58.3) | ≥80 | 226 (21.8) | 353 (17.1) | Sex | | | Female | 278 (26.9) | 629 (30.4) | Male | 757 (73.1) | 1439 (69.6) | Year of diagnosis | | | 2010 | 151 (14.6) | 370 (17.9) | 2011 | 153 (14.8) | 338 (16.3) | 2012 | 188 (18.2) | 310 (15.0) | 2013 | 152 (14.7) | 342 (16.5) | 2014 | 181 (17.5) | 342 (16.5) | 2015 | 210 (20.3) | 366 (17.7) | Race | | | White | 878 (84.8) | 1781 (86.1) | Black | 108 (10.4) | 185 (8.9) | Other | 49 (4.7) | 102 (4.9) | Histology | | | Transitional cell carcinoma | 1001 (96.7) | 1953 (94.4) | No transitional cell carcinoma | 34 (3.3) | 115 (5.6) | T stage | | | T0 | 9 (0.9) | 6 (0.3) | T1 | 141 (13.6) | 102 (4.9) | T2 | 456 (44.1) | 618 (29.9) | T3 | 97 (9.4) | 671 (32.4) | T4 | 196 (18.9) | 604 (29.2) | TX | 136 (13.1) | 67 (3.2) | N stage | | | N0 | 569 (55.0) | 289 (14.0) | N1 | 103 (10.0) | 694 (33.6) | N2 | 173 (16.7) | 830 (40.1) | N3 | 56 (5.4) | 212 (10.3) | NX | 134 (12.9) | 43 (2.1) | Grade | | | I–II | 18 (1.7) | 33 (1.6) | III–IV | 819 (79.1) | 1855 (89.7) | Unknown | 198 (19.1) | 180 (8.7) | Surgery primary site | | | None | 227 (21.9) | 153 (7.4) | TURB | 638 (61.6) | 597 (28.9) | Partial cystectomy | 5 (0.5) | 39 (1.9) | Radical cystectomy | 31 (3.0) | 536 (25.9) | Pelvic exenteration | 34 (3.3) | 638 (30.9) | Other | 100 (9.7) | 105 (5.1) |
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UBUC, urinary bladder urothelial carcinoma; TURB, transurethral resection of the bladder.
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