Expression Profiles of HOXC6 Predict the Survival of Glioblastoma Patients and Correlate with Cell Cycle

Figure 1

(a) Gene expression analysis of 33 HOX genes from 535 samples of TCGA microarray dataset identified 14 differentially expressed genes. The columns represent samples, and rows represent the score of the gene expression value. Color bar: red indicates high relative expression levels, whereas green indicates low levels. Vertical bar: red indicates upregulated genes, green indicates downregulated genes, and gray indicates no difference. Horizontal bar: blue indicates GBM tissues, whereas yellow indicates normal brain tissues (NBT). (b) Distribution of HOX genes based on differential expression gene analysis and univariate Cox regression analysis. HR: hazard ratio; Log2(FC): log2 value of fold change; FDR: false discovery rate of value in the differential expression gene analysis. Blue balls indicate genes that are not differentially expressed, whereas red balls indicate genes that are differentially expressed. The left top red ball indicates HOXC6.

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