Expression Profiles of HOXC6 Predict the Survival of Glioblastoma Patients and Correlate with Cell Cycle

Figure 2

HOXC6 expression profile predicted the survival of GBM patients in different datasets. (a-c) TCGA microarray dataset. (a) Gaussian mixture modeling to identify bimodal expression patterns. (b) Expression profile of HOXC6 in normal brain tissue (NBT), low-expression group (low) and high-expression group (high) was analyzed using the Student -test. (c) Kaplan–Meier survival analyses based on the cutoff of HOXC6 expression value in the TCGA microarray dataset. (d-f) TCGA RNA-seq dataset. (d) Gaussian mixture modeling to identify bimodal expression patterns. (e) Expression profile of HOXC6 among normal brain tissue (NBT), low-expression group (low), and high-expression group (high) was analyzed using the Student -test. (f) Kaplan–Meier survival analyses based on the cutoff of HOXC6 expression value in the TCGA RNA-seq dataset. (g-i) GSE16011 dataset. (g) Gaussian mixture modeling to identify bimodal expression patterns. (h) Expression profile of HOXC6 among normal brain tissue (NBT), low-expression group (low), and high-expression group (high) was analyzed using the Student -test. (i) Kaplan–Meier survival analyses based on the cutoff of HOXC6 expression value in the GSE16011 dataset. NS. ; ; ; .

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