Expression Profiles of HOXC6 Predict the Survival of Glioblastoma Patients and Correlate with Cell Cycle
Table 1
Cox regression analysis of HOXC6 and other characteristics in GBM.
Variables
TCGA microarray Univariate
TCGA microarray Multivariate
TCGA RNA-seq Multivariate
GSE16011 Multivariate
HR
HR
HR
HR
HOXC6
1.47
0.0013
1.27
0.0481
1.82
0.0074
1.49
0.0486
Age
1.64
<0.0001
1.52
<0.0001
1.26
0.0899
1.19
0.1156
Sex
1.16
0.1223
1.16
0.1322
0.94
0.7655
1.07
0.7198
Chemotherapy
0.41
<0.0001
0.68
0.0168
0.43
0.0831
0.52
0.0982
Radiotherapy
0.35
<0.0001
0.52
0.0001
0.18
0.0004
0.42
0.0002
Hazard ratio for age variable: risk per 20 years. HR: hazard ratio; univariate: univariate Cox regression; multivariate: multivariate Cox regression; NA: not acquired.