A New Model for Predicting Nonsentinel Lymph Node Metastasis in Early-Stage Breast Cancer Using MMP15

Figure 3

Nomogram to predict the probability of nonsentinel lymph node (NSLN) metastasis in sentinel lymph nodes (SLNs)-positive breast cancer patients. The new model included five variables: matrix metalloproteinase 15 (MMP15) expression in the cytoplasm, number of positive SLNs, neural invasion, tumor size, and lymphovascular invasion. After each variable was assigned, it corresponded to the score of the first row in the nomogram and then the five scores were summed to get the total score. From this score, the NSLN metastasis probability could be obtained.