A New Model for Predicting Nonsentinel Lymph Node Metastasis in Early-Stage Breast Cancer Using MMP15
Table 3
Multivariate logistic regression analysis of factors related to NSLN metastases.
Variables
value
OR
95% CI
Lower
Upper
Tumor size (cm)
0.011
1.899
1.157
3.117
Lymphovascular invasion
Yes versus no
0.048
2.455
1.008
5.981
Neural invasion
Yes versus no
0.003
40.935
3.665
457.198
Expression of MMP15 in cytoplasm
Positive versus negative
≤0.001
4.912
2.083
11.585
Number of positive SLNs
0.038
2.47
1.054
5.789
Number of negative SLNs
0.483
0.825
0.481
1.413
Percentage of positive SLNs
0.714
0.361
0.002
84.504
NLR
0.124
0.64
0.362
1.131
SLNs, sentinel lymph nodes; MMP15, matrix metalloproteinase 15; NLR, the ratio of the absolute number of neutrophils to the absolute number of lymphocytes.
