Eupalinolide O Induces Apoptosis in Human Triple-Negative Breast Cancer Cells via Modulating ROS Generation and Akt/p38 MAPK Signaling Pathway

Figure 4

EO induced human TNBC cells apoptosis by intrinsic pathway. MMP loss (a) and caspase-3 expression (b) in TNBC cells evaluated by flow cytometry. (c) PARP and caspase-3 and -9 mRNA expression tested by qRT-PCR. . MMP, mitochondrial membrane potential.

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