Research Article
FECH Expression Correlates with the Prognosis and Tumor Immune Microenvironment in Clear Cell Renal Cell Carcinoma
Table 3
Results of gene ontology enrichment analysis.
| Ontology | ID | Description | Gene Ratio | Bg Ratio | P value | P. adjust | Q value |
| BP | GO:0002526 | Acute inflammatory response | 21/96 | 220/18670 | 4.30e−21 | 6.40e−18 | 5.33e−18 | BP | GO:0006953 | Acute-phase response | 10/96 | 47/18670 | 3.53e−14 | 2.63e−11 | 2.19e−11 | BP | GO:0072376 | Protein activation cascade | 12/96 | 198/18670 | 4.16e−10 | 1.55e−07 | 1.29e−07 | BP | GO:2000257 | Regulation of protein activation cascade | 10/96 | 116/18670 | 4.17e−10 | 1.55e−07 | 1.29e−07 | BP | GO:0006956 | Complement activation | 11/96 | 175/18670 | 1.58e−09 | 4.71e−07 | 3.93e−07 | CC | GO:0072562 | Blood microparticle | 15/101 | 147/19717 | 1.02e−15 | 1.56e−13 | 1.31e−13 | CC | GO:0034364 | High-density lipoprotein particle | 9/101 | 26/19717 | 4.90e−15 | 3.78e−13 | 3.17e−13 | CC | GO:0034358 | Plasma lipoprotein particle | 9/101 | 37/19717 | 1.86e−13 | 7.18e−12 | 6.03e−12 | CC | GO:1990777 | Lipoprotein particle | 9/101 | 37/19717 | 1.86e−13 | 7.18e−12 | 6.03e−12 | CC | GO:0032994 | Protein-lipid complex | 9/101 | 39/19717 | 3.15e−13 | 9.70e−12 | 8.15e−12 | MF | GO:0043178 | Alcohol binding | 7/94 | 85/17697 | 3.35e−07 | 7.77e−05 | 6.03e−05 | MF | GO:0017127 | Cholesterol transporter activity | 4/94 | 18/17697 | 2.16e−06 | 1.44e−04 | 1.12e−04 | MF | GO:0120020 | Intermembrane cholesterol transfer activity | 4/94 | 18/17697 | 2.16e−06 | 1.44e−04 | 1.12e−04 | MF | GO:0120015 | Intermembrane sterol transfer activity | 4/94 | 19/17697 | 2.72e−06 | 1.44e−04 | 1.12e−04 | MF | GO:0034987 | Immunoglobulin receptor binding | 6/94 | 76/17697 | 3.10e−06 | 1.44e−04 | 1.12e−04 | KEGG | hsa04979 | Cholesterol metabolism | 5/38 | 50/8076 | 3.19e−06 | 2.78e−04 | 2.52e−04 | KEGG | hsa03320 | PPAR signaling pathway | 4/38 | 78/8076 | 4.63e−04 | 0.019 | 0.017 | KEGG | hsa04610 | Complement and coagulation cascades | 4/38 | 85/8076 | 6.42e−04 | 0.019 | 0.017 | KEGG | hsa04975 | Fat digestion and absorption | 3/38 | 43/8076 | 0.001 | 0.023 | 0.021 | KEGG | hsa04977 | Vitamin digestion and absorption | 2/38 | 24/8076 | 0.006 | 0.097 | 0.088 |
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