Identification and Validation of a Novel Multiomics Signature for Prognosis and Immunotherapy Response of Endometrial Carcinoma

Figure 2

Differential expression and function enrichment analysis. (a) Heatmap of 457 DEGs (differentially expressed genes) between tumor and normal samples. (b) Volcano-plot of 746 differential CpG sites, 3 most upregulated sites marked. (c) Bimodal distribution of Beta value for methylation among tumor and normal samples. (d) KEGG and GO enrichment analysis. (e) Top 30 mutant genes in EC. (f) TOP 30 genes with copy number variance. (UP: upregulated DEGs; DOWN: downregulated DEGs, KEGG : Kyoto Encyclopedia of Genes and Genomes; GO : Gene Ontology).

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