Identification and Validation of a Novel Multiomics Signature for Prognosis and Immunotherapy Response of Endometrial Carcinoma

Figure 3

Construction and evaluation of the prognostic signature. (a) Most factors’ coefficients were penalized toward zero by LASSO regression. (b) 22 variables were screened out with a minimal partial likelihood deviance. (c) Patients’ survival status, ranking by their risk score. (d) Survival analysis between high-risk and low-risk group. (e) Risk score out-weights common clinical features in predicting patients’ survival with higher AUC of 0.788. (f) (g) Univariate and multivariate Cox regression demonstrated the prognostic signature can be an independent prognostic factor. (AUC : Area under the curve; BMI : Body mass index).

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