Synergistic Lethality Effects of Apatinib and Homoharringtonine in Acute Myeloid Leukemia

Table 1

IC₅₀ values of Apatinib and HHT as single agent in AML cells.

AML cell lines	IC50 at 24 h		IC50 at 48 h
	Apa (μM)	HHT (nM)	Apa (μM)	HHT (nM)
MV4-11	6.76 ± 1.14	15.2 ± 1.80	4.67 ± 0.81	6.05 ± 1.31
MOLM-13	4.11 ± 0.81	12.2 ± 2.83	2.25 ± 1.22	5.30 ± 1.04
OCI-AML2	101.1 ± 11	16.2 ± 0.89	31.2 ± 15.8	7.69 ± 1.28
OCI-AML3	4.97 ± 1.30	15.93 ± 1.17	3.23 ± 0.56	5.51 ± 0.91