The Interaction of the IFNγ/JAK/STAT1 and JAK/STAT3 Signalling Pathways in EGFR-Mutated Lung Adenocarcinoma Cells

Figure 5

Inhibition of STAT3 phosphorylation further activates the IFNγ/JAK/STAT1 signalling pathway. (a)–(d) The relative proteins expressions of difference groups in NSCLC cells (H1299, PC-9, H1975 and H3255) by western blotting assay. (e)–(h) qRT-PCR was used to analyse the mRNA expression levels of relative genes in NSCLC cells (H1299, H1975, PC9, H3255) treated combined with or without IFNγ/STAT3 inhibitor. All data were illustrated as mean ± SD and the asterisks show significant difference.

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