circPOLR1C Promotes the Development of Esophageal Cancer by Adsorbing miR-361-3p and Regulating Cancer Cell Apoptosis and Metastasis

Figure 7

Effects of the miR-361-3p mimic and overexpressed circPOLR1C on the growth and apoptosis-related gene expressions in transplanted tumors in vivo. (a)–(f) The effects of the miR-361-3p mimic and circPOLR1C on the volume and weight of the transplanted tumors. (g) The effects of the miR-361-3p mimic and circPOLR1C on the mRNA levels of apoptosis-related genes were assessed by qRT-PCR. GAPDH was applied as the internal reference. (h)–(i) The effects of the miR-361-3p mimic and circPOLR1C on the protein levels of apoptosis-related genes were evaluated by Western blot. GAPDH was employed as the internal reference, n = 6/group. All experiments were independently carried out in triplicate. ; vs. NC + MC; ^ ^ ^ vs. NC + M; ^### vs. circPOLR1C + MC.

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