Review Article
YTHDC2 Promotes Malignant Phenotypes of Breast Cancer Cells
Table 1
Association between YTHDC2 expression and clinicopathological parameters.
| Variable | | YTHDC2 expression | value | 0 | 1+ | 2+ | 3+ |
| All cases | 99 | 28 | 36 | 15 | 20 | | Age (years) | | | | | | | ≤60 | 43 | 14 | 14 | 9 | 6 | 0.413† | >60 | 56 | 14 | 22 | 6 | 14 | | Stage | | | | | | | I | 49 | 17 | 18 | 9 | 5 | 0.032‡ | IIA | 30 | 7 | 11 | 3 | 9 | | IIB | 6 | 3 | 1 | 0 | 2 | | IIIA | 1 | 0 | 1 | 0 | 0 | | IIIB | 6 | 1 | 3 | 1 | 1 | | IIIC | 3 | 0 | 1 | 2 | 0 | | IV | 4 | 0 | 1 | 0 | 3 | | Subtype | | | | | | | Luminal A | 31 | 11 | 8 | 6 | 6 | 0.882† | Luminal B | 46 | 10 | 20 | 8 | 8 | | HER2 enriched | 9 | 2 | 4 | 0 | 3 | | Triple negative | 13 | 5 | 4 | 1 | 3 | | ER | | | | | | | Negative | 22 | 7 | 8 | 1 | 6 | 0.878† | Positive | 77 | 21 | 28 | 14 | 14 | | PgR | | | | | | | Negative | 38 | 12 | 16 | 3 | 7 | 0.295† | Positive | 61 | 16 | 20 | 12 | 13 | | HER2 | | | | | | | Negative | 85 | 23 | 30 | 15 | 17 | 0.402† | Positive | 14 | 5 | 6 | 0 | 3 | |
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†Determined using the Kruskal–Wallis test; ‡determined using the Spearman rank correlation coefficient.
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