Research Article

Assessment of Cone-Beam Breast Computed Tomography for Predicting Pathologic Response to Neoadjuvant Chemotherapy in Breast Cancer: A Prospective Study

Table 1

Baseline characteristics of patients.

CharacteristicspCR ()Non-pCR () value

Side
Left15 (41.7)19 (42.2)0.594
Right21 (58.3)26 (57.8)
Age (years)0.003
Body mass index0.806
Low2 (5.6)3 (0.6)
Normal24 (66.7)30 (66.7)
Obesity8 (22.2)10 (22.2)
Overweight2 (5.6)2 (0.5)
Menopausal status0.447
Premenopausal30 (83.3)37 (82.2)
Postmenopausal6 (16.7)8 (17.8)
Family history0.786
With7 (19.4)9 (20.0)
Without29 (80.6)36 (80.0)
Therapy0.078
Doxorubicin0 (0)0 (10.3)
Paclitaxel without trastuzumab target22 (61.1)27 (51.7)
Paclitaxel with trastuzumab target14 (38.9)18 (37.9)
Tumor baseline size (mm)32.4 (24.5, 48.1)44.6 (29.2, 58.1)0.067
Histologic type0.246
Ductal carcinoma in situ1 (2.8)1 (2.2)
Invasive ductal carcinoma34 (94.4)43 (95.6)
Mixing invasive carcinoma1 (2.8)1 (2.2)
Hormone receptor0.981
Positive negative15 (41.7)1832 (40.071.1)
Negative positive21 (58.3)2713 (6028.9.0)
HER20.951
Negative6 (16.7)7 (15.6)
Positive30 (83.3)38 (84.4)
Ki-67 receptor0.197
Low2 (5.6)3 (6.7)
High34 (94.4)42 (93.3)
Complications0.439
With7 (19.4)9 (20.0)
Without29 (80.6)36 (80.0)

Note: The data reveals numbers of patients in the pCR and non-pCR group with percentages in parentheses or . values marked asterisk present significant statistical value. pCR: Pathologic complete response; HER: Human epidermal growth factor receptor.