Assessment of Cone-Beam Breast Computed Tomography for Predicting Pathologic Response to Neoadjuvant Chemotherapy in Breast Cancer: A Prospective Study

Table 2

CBBCT parameters before and during NAC.

Parameters	Pre-NAC	value	Mid-NAC	value	Late-NAC	value
Lesion density/HU		0.999		0.671		0.756
One-min enhancement/HU		0.794		0.156		0.001
Two-min enhancement/HU		0.898		0.007		0.001
Three-min enhancement/HU		0.621		0.046		0.011
Diameter/mm		0.064		0.006		0.012
Volume/mm^2		0.062		0.002		0.017
Segmented volume/mm^3		0.082		0.004		<0.001
Segmented surface area/mm^2		0.072		0.013		<0.001
Washout rate (%/s)		0.422		0.056		0.622
Maximum enhancement ratio (%)		0.97		0.023		<0.001
Wash-in rate (%/s)		0.921		0.034		<0.001

Note: The numbers in the table represent mean with standard deviation. values with statistical value are marked with asterisk. HU: Hounsfield unit. CBBCT: Cone-beam breast computed tomography. NAC: Neoadjuvant chemotherapy.