Assessment of Cone-Beam Breast Computed Tomography for Predicting Pathologic Response to Neoadjuvant Chemotherapy in Breast Cancer: A Prospective Study
Table 3
Univariable and multivariable regression analysis of CBBCT parameters in late-NAC.
Univariable analysis of CBBCT parameters in late-NAC
Multivariable analysis of CBBCT parameters in late-NAC
OR
SE
p value
OR
SE
value
(Reference)
1
1
Hormone status
0.269 (0.096,0.755)
0.527
0.013
One-min enhancement/HU
0.990 (0.980, 1.000)
0.005
0.048
Two-min enhancement/HU
0.986 (0.976, 0.996)
0.005
0.007
Three-min enhancement/HU
0.984 (0.972, 0.996)
0.006
0.008
Wash-in rate (%/s)
4.293 (1.770, 10.413)
0.452
0.001
Maximum enhancement ratio (%)
2.667 (1.620, 4.390)
0.254
<0.001
2.192 (1.338, 3.590)
0.252
0.002
Diameter/mm
0.946 (0.903, 0.991)
0.024
0.020
Segmented volume/mm3
2.833 (1.633, 4.916)
0.281
<0.001
Segmented surface area/mm2
1.967 (1.278, 3.028)
0.220
0.002
Segmented volume reduction (%)
0.264 (0.111, 0.628)
0.441
0.003
0.319 (0.122, 0.836)
0.492
0.02
Segmented surface area reduction (%)
0.468 (0.286, 0.764)
0.25
0.002
Note: The numbers in the table represent point estimate with 95% confidence intervals. values with statistical value are marked with asterisk. HU: Hounsfield unit. OR: odds ratio. SE: Standard error. CBBCT: cone-beam breast computed tomography. NAC: Neoadjuvant chemotherapy.
