Research Article
Aberrant ARMCX1 Expression Is an Independent Predictor of Poor Prognosis in Gastric Cancer
Table 2
Logistic regression of NUDT10 expression and clinicopathological parameters in TCGA and our validation cohort.
| TCGA cohort | TN | OR | 95% CI | value | Clinical features |
| Age | ≥65 vs. <65 | 371 | 0.611 | 0.403-0.922 | 0.193 | Gender | Female vs. male | 375 | 0.946 | 0.620-1.444 | 0.799 | Grade | G2 vs. G1 | 146 | 0.638 | 0.157-2.332 | 0.501 | G3 vs. G1 | 229 | 0.991 | 0.269-3.655 | 0.989 | T stage | T2 vs. T1 | 99 | 7.216 | 2.191-32.814 | 0.003 | T3 vs. T1 | 187 | 6.154 | 1.961-27.163 | 0.005 | T4 vs. T1 | 119 | 24.857 | 4.839-455.953 | 0.002 | LN metastasis | Yes vs. no | 357 | 0.717 | 0.456-1.123 | 0.147 | Distant metastasis | Yes vs. no | 355 | 1.866 | 0.817-4.522 | 0.148 | TNM stage | Stage II vs. stage I | 164 | 2.088 | 1.076-4.129 | 0.031 | Stage III vs. stage I | 203 | 2.409 | 1.267-4.706 | 0.008 | Stage IV vs. stage I | 91 | 2.612 | 1.120-6.286 | 0.028 | Validation cohort | | | | | Age | ≥65 vs. <65 | 52 | 2.576 | 0.854-8.171 | 0.098 | Gender | Female vs. male | 52 | 1.437 | 0.441-4.837 | 0.549 | Grade | G3 VS G1 + G2 | 52 | 0.858 | 0.285-2.554 | 0.781 | Tumor size | ≥5 cm vs. <5 cm | 52 | 0.629 | 0.206-1.871 | 0.406 | T stage | T4 VS T1 + T2 + T3 | 52 | 9.048 | 2.718-34.458 | <0.001 | LN metastasis | Yes vs. no | 52 | 3.600 | 1.173-11.852 | 0.029 | TNM stage | Stage III vs. stage I/II | 52 | 3.600 | 1.173-11.852 | 0.029 |
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Abbreviations: OR: odds ratio; TN: total number; CI, confidence interval; LN: lymph node. Italics indicate statistical significance of expression level with , , . |