Assessing the Variations in Breast/Ovarian Cancer Risk for Chinese BRCA1/2 Carriers

Table 1

Clinical characteristics and germline BRCA1/2 status of the samples in this study.

Cancer site	Number, n = 7919 (%)	Median age (years)	value	BRCA1/2 carriers, n = 729 (%)	Non-carriers, n = 7190	value
Breast	2400 (30.31%)	45.00 (38.00–52.00)	<0.0001	285 (11.88%)	2115 (88.13%)	0.041
Ovary	1697 (21.43%)	52.00 (46.00–59.00)		332 (19.32%)	1365 (80.68%)
Breast and ovary	32 (0.40%)	55.00 (48.25–60.75)		16 (48.48%)	16 (51.52%)
Breast or ovary and other sites	33 (0.42%)	53.50 (45.00–61.00)		1 (3.03%)	32 (96.97%)
Other sites	116 (1.46%)	61.00 (49.25–70.75)		5 (4.31%)	111 (95.69%)
Cancer-free	3641 (45.98%)	36.00 (30.00–43.00)		90 (2.47%)	3551 (97.53%)