Assessing the Variations in Breast/Ovarian Cancer Risk for Chinese BRCA1/2 Carriers

Table 3

Age estimation analysis using population data from different historical time points.

Time point	Population (thousand)	Average growth rate (‰)	Time till now (yrs)	Estimated mutation age (yrs)
684 B.C.	11,840	1.76	2,704	2,145
2 A.D.	59,590	1.54‰	2,018	2,090
609 A.D.	46,020	2.40‰	1,411	1,534
1110 A.D.	46,730	3.71‰	910	1,585
1403 A.D.	66,600	4.87‰	617	992
1741 A.D.	143,410	7.81‰	279	602
1949 A.D.	541.67	6.50‰	71	1,006