Combining Organoid Models with Next-Generation Sequencing to Reveal Tumor Heterogeneity and Predict Therapeutic Response in Breast Cancer

Table 2

Single gene mutation.

	Chromosome	Location	Transcripts	Nucleotides	Amino acids
RET	chr10	43606832	NM_020975.4	c.1441 C > G	p.Leu481Val
AXIN2	chr17	63533506	NM_004655.3	c.1648 T > G	p.Tyr550Asp
BAP1	chr3	52438553	NM_004656.3	c.1166 G > A	p.Arg389His
TP53	chr17	7573985	NM_000546.5	c.1041del	p.L348Wfs 22
PIK3CA	chr3	178952085	NM_006218.2	c.3140 A > G	p.H1047R
PPP2R2A	chr8	26217786	NM_001177591.1	c.479-484delCTACACinsTG	p.T160Mfs 12