NF-κB-Activated lncRNACASC9 Promotes Bladder Cancer Progression by Regulating the TK1 Expression

Figure 5

CASC9 promotes BC cells growth and metastasis in vivo. (a) The CASC9 expression was detected in sh-CASC9 stably transfected 5637 by qRT-PCR. (b) The CASC9 stably knock down group or the negative control was used for tumorigenesis assay. One month later, the mice were euthanized, and the tumor nodules were harvested. Tumor growth curves are shown. (c) Representative images of lungs (left) from mice after tail vein injections with stably transfected sh-CASC9 and sh-NC cells. Representative images of H&E staining (middle) and computerized tomography (CT) scan (right). (d) Quantitative analysis of metastasis foci in corresponding groups. (e) Survival analysis of mice after tail vein injections with stably transfected sh-CASC9 and sh-NC cells. , , and .

(a)

(b)

(c)

(d)

(e)