IRF2 Destabilizes Oncogenic KPNA2 to Modulate the Development of Osteosarcoma

Figure 4

KPNA2 promoted the activation of EMT through IRF2. (a) The cell migration capacity of OS cells was examined using wound healing assays at 0 and 24 h. (b) Cells were stained with 0.1% crystal violet (left) . Cell numbers were quantified to value the invasive capacity of OS cells after different transfection (right). (c) Protein levels of EMT-related proteins (E-cadherin, N-cadherin, and Vimentin) in two OS cells (MG-63 and U2OS). Data were presented as from three independent experiments , , and .

(a)

(b)

(c)