The Effects of circ_000558/miR-1225-5p/ARL4C on Regulating the Proliferation of Renal Cell Carcinoma Cells

Figure 2

The effects of circ_000558 on cell proliferation and apoptosis in RCC cells. (a) The expression of circ_000558 in 769-P and ACHN cells after transfected with si-NC and si-circ_000558 (si-circ) was tested by qPCR analysis. (b) The inhibitor rate of cell proliferation in 769-P and ACHN cells after si-NC and si-circ transfection was measured using CCK-8 assay. (c) The cell apoptosis in 769-P and ACHN cells after si-NC and si-circ transfection was detected by flow cytometry. (d) The protein expression of apoptosis related protein (Bcl-2, Bax, and cleaved caspase-3) was analyzed by western blot assay ( < 0.05,  < 0.01, and  < 0.001).

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