Research Article

IGFBP3 Enhances Treatment Outcome and Predicts Favorable Prognosis in ABC-DLBCL

Table 2

Correlations between the expression level of IGFBP3 and clinicopathological factors in ABC-DLBCL patients from the GEO database.

VariablesExpression level of IGFBP3 value
LowHigh

Age0.159
≤602028
>605345

Sex0.238
Female3326
Male4047

Stage0.020
I-II2539
III-IV4834

Extranodal infiltration0.033
≤15061
>12312

ECOG score0.442
≤15357
>12016

LDH0.011
Normal2237
Elevated5136

IPI score0.007
≤23652
>23721

Treatment response0.706
CR5355
Non-CR2018

ECOG, eastern cooperative oncology group performance status; LDH, lactate dehydrogenase; IPI, international prognostic index; CR, complete response; non-CR, partial response, stable disease, progressive disease; bold, significant difference.