Extracellular Volume Fraction Calculated Using Contrast-Enhanced Computed Tomography as a Biomarker of Oxaliplatin-Induced Sinusoidal Obstruction Syndrome: A Preliminary Histopathological Analysis

Figure 3

Sinusoidal congestion was graded from 0 to 3 according to the severity of the findings, as proposed in the original publication by Rubbia-Brandt et al., in which (a) grade 0 = absent, (b) grade 1 = mild (centrilobular involvement limited to one-third of the lobular surface), and (c) grade 2 = moderate (centrilobular involvement extending in two-thirds of the lobular surface). Scale bar 100 μm.