Extracellular Volume Fraction Calculated Using Contrast-Enhanced Computed Tomography as a Biomarker of Oxaliplatin-Induced Sinusoidal Obstruction Syndrome: A Preliminary Histopathological Analysis

Figure 4

Perisinusoidal fibrosis was analyzed with Masson trichrome-stained slides and graded from 0 to 2 as follows: (a) grade 0 = absent; (b) grade 1 = mild (<50% sinusoids evaluated on 20 fields at ×200 magnification); and (c) grade 2 = moderate (>50% sinusoids evaluated on 20 fields at ×200 magnification). Scale bar 50 μm.