Silencing UBQLN2 Enhances the Radiosensitivity of Esophageal Squamous Cell Carcinoma (ESCC) via Activating p38 MAPK

Figure 4

RNA-sequencing results. (a) Volcano plot displaying upregulated or downregulated genes in Ec109 cells in response to UBQLN2 knockdown. (b) Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were significantly enriched for upregulated genes in UBQLN2 knockdown Ec109 cells. (c) Gene set enrichment analysis (GSEA) analysis also identified the mitogen-activated protein kinases (MAPK) signaling pathway as a regulatory target of UBQLN2 in RNA-sequencing data.

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