Tracking Peripheral Memory T Cell Subsets in Advanced Nonsmall Cell Lung Cancer Treated with Hypofractionated Radiotherapy and PD-1 Blockade

Figure 1

Peripheral immune memory T cell subsets in untreated NSCLC patients (n = 17) show stronger immune memory effects than those in healthy donors (n = 20). (a) Gating scheme for memory T cell subpopulations in PBMCs. (b) Differences in naïve (Tn), central memory (Tcm), effector memory (Tem), and effector memory RA (TemRA) T cells among CD4⁺ and CD8⁺ T cells between NSCLC patients and healthy controls. (c) CD4⁺PD-1⁺ and CD8⁺PD-1⁺ T cell subpopulations among PBMCs from NSCLC patients and healthy controls. HD, healthy donors; Pt, patients. Data are shown as the mean ± SD, , , , , and ns, not significant.

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