TREM2 as a Prognostic Biomarker for Osteosarcoma Microenvironment Remodeling

Figure 3

Heatmaps, Venn plots, and enrichment analysis of GO and KEGG for DEGs. (a, b) Heatmap for DEGs generated by comparison of the high-score group vs. the low-score group in ImmuneScore and StromalScore, respectively. Row name of heatmap is the gene name, and column name is the ID of samples which not shown in plot. Differentially expressed genes were determined by Wilcoxon rank sum test with q = 0.05 and fold change >1. (c, d) Venn plots showing common upregulated and downregulated DEGs shared by ImmuneScore and StromalScore, and q < 0.05 and fold change >1 as the DEGs significance filtering threshold. (e, f) GO and KEGG enrichment analysis for 118 DEGs, terms with p and q < 0.05 were considered to be enriched significantly.

(a)

(b)

(c)

(d)

(e)

(f)