The High Expression of p53 Is Predictive of Poor Survival Rather TP53 Mutation in Esophageal Squamous Cell Carcinoma

Figure 2

Immunohistochemical staining scoring criteria for p53 protein in ESCC (A, D, G, J, M, P, S, V, magnification ×80, B, E, H, K, N, Q, T, W, magnification ×200, C, F, I, L, O, R, U, X, magnification ×400). (a–l) Scoring criteria of pattern of immunostaining: (a–c) entirely negative staining; (d–f) scattered; (g–i) focal; (j–l) diffuse. (m–x) Scoring criteria of intensity of immunostaining: (m–o) negative staining; (p–q) weak staining; (s–u) moderate staining; (v–x) strong staining.

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