The High Expression of p53 Is Predictive of Poor Survival Rather TP53 Mutation in Esophageal Squamous Cell Carcinoma

Figure 5

Kaplan–Meier curves survival analysis of ESCC patients with different TP53 mutations and p53 protein expression. (a) OS of TP53 mutation and wild-type in 316 patients with sequencing data. (b) OS of p53 protein high and low expression in 276 patients who have TP53 mutation and p53 protein expression. (c) OS of different types of mutation in 316 patients with sequencing data. (d) OS of nonhotspot and hotspot mutation in 135 patients who have missense mutation. (e) OS of different groups of TP53 mutation status/p53 protein expression in 276 patients who have TP53 mutation and p53 protein expression. (f) OS of p53 protein high and low expression in 6,028 patients who have p53 expression in TMAs.

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