Research Article
The High Expression of p53 Is Predictive of Poor Survival Rather TP53 Mutation in Esophageal Squamous Cell Carcinoma
Table 3
Characteristics of the ESCC patients undergoing TP53 mutation detection.
| | No | Patient ID | Sex | Age | UICC stage | Sequence source | Mutation status | Number of mutations | p53 IHC (positive/negative) | p53 IHC (low/high) | Survival status | Survival time (years) |
| | 1 | CE12T | M | 72 | IVB | WES | TP53 wild-type | 0 | Positive | Low | Dead | 1.70 | | 2 | CE18T | M | 50 | III | WES | TP53 mutation | 1 | Negative | Low | Dead | 4.73 | | 3 | CE16T | M | 69 | IIA | WES | TP53 wild-type | 0 | Positive | Low | Dead | 1.81 | | 4 | CE4T | M | 64 | IIB | WES | TP53 mutation | 1 | Negative | Low | Dead | 3.95 | | 5 | CE7T | M | 70 | III | WES | TP53 mutation | 1 | Positive | Low | Dead | 5.00 | | 6 | CE15T | M | 57 | III | WES | TP53 mutation | 1 | Positive | Low | Dead | 5.81 | | 7 | CE30T | M | 56 | IIA | WES | TP53 wild-type | 0 | Negative | Low | Alive | 10.51 | | 8 | CE20T | M | 72 | IIA | WES | TP53 mutation | 1 | Positive | Low | Dead | 4.07 | | 9 | CE26T | M | 71 | III | WES | TP53 mutation | 2 | Positive | High | Dead | 6.16 | | 10 | CE5T | F | 75 | III | WES | TP53 mutation | 1 | Positive | Low | Dead | 5.11 | | 11 | CE25T | M | 64 | IIA | WES | TP53 wild-type | 0 | Positive | High | Dead | 2.05 | | 12 | CE24T | M | 58 | IIA | WES | TP53 mutation | 1 | Positive | High | Alive | 11.04 | | 13 | CE21T | M | 54 | IIA | WES | TP53 mutation | 2 | Negative | Low | Dead | 6.50 | | 14 | CE27T | M | 64 | III | WES | TP53 mutation | 1 | Positive | High | Dead | 2.41 | | 15 | EC888T | M | 59 | III | TRS | TP53 wild-type | 0 | Positive | High | Alive | 5.05 | | 16 | EC889T | M | 62 | III | TRS | TP53 mutation | 1 | Positive | High | Dead | 0.79 | | 17 | EC891T | M | 55 | IIB | TRS | TP53 wild-type | 0 | Negative | Low | Dead | 1.75 | | 18 | EC892T | M | 60 | III | TRS | TP53 mutation | 1 | Positive | High | Dead | 3.15 | | 19 | EC893T | F | 64 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 4.71 | | 20 | EC1038T | M | 74 | IV | TRS | TP53 mutation | 1 | Positive | Low | Dead | 1.49 | | 21 | EC1035T | M | 65 | III | TRS | TP53 wild-type | 0 | Positive | High | Dead | 2.27 | | 22 | EC1032T | F | 51 | IIA | TRS | TP53 mutation | 1 | Positive | High | Dead | 2.27 | | 23 | EC632T | M | 59 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 4.78 | | 24 | EC636T | M | 64 | IIB | TRS | TP53 mutation | 1 | Negative | Low | Alive | 4.77 | | 25 | EC090T | M | 47 | III | WES | TP53 mutation | 1 | Positive | High | Alive | 1.41 | | 26 | EC633T | F | 63 | I | TRS | TP53 mutation | 1 | Positive | Low | Alive | 4.80 | | 27 | EC640T | M | 58 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 4.81 | | 28 | EC643T | F | 67 | IIA | TRS | TP53 mutation | 1 | Positive | Low | Dead | 2.54 | | 29 | EC644T | M | 61 | III | TRS | TP53 mutation | 1 | Negative | Low | Dead | 2.33 | | 30 | EC641T | F | 60 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 4.84 | | 31 | EC967T | M | 69 | IIA | TRS | TP53 mutation | 2 | Negative | Low | Alive | 4.84 | | 32 | EC968T | F | 63 | IIA | TRS | TP53 mutation | 1 | Positive | Low | Alive | 4.85 | | 33 | EC966T | M | 69 | IIA | TRS | TP53 mutation | 2 | Positive | High | Dead | 2.37 | | 34 | EC965T | F | 71 | IIA | TRS | TP53 mutation | 1 | Positive | High | Dead | 0.95 | | 35 | EC1024T | F | 65 | IVA | TRS | TP53 mutation | 1 | Positive | Low | Dead | 4.03 | | 36 | EC190T | M | 50 | IIA | WES | TP53 mutation | 2 | Positive | Low | Alive | 10.80 | | 37 | EC969T | M | 63 | III | TRS | TP53 mutation | 1 | Positive | High | Alive | 4.88 | | 38 | EC970T | M | 66 | III | TRS | TP53 wild-type | 0 | Negative | Low | Dead | 0.13 | | 39 | EC971T | M | 66 | III | TRS | TP53 mutation | 1 | Negative | Low | Alive | 5.21 | | 40 | EC973T | F | 63 | IIB | TRS | TP53 mutation | 1 | Negative | Low | Dead | 0.88 | | 41 | EC975T | M | 62 | III | TRS | TP53 mutation | 1 | Positive | Low | Alive | 4.88 | | 42 | EC976T | F | 79 | IIA | TRS | TP53 mutation | 1 | Positive | Low | Dead | 1.89 | | 43 | EC978T | M | 57 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 5.26 | | 44 | EC981T | M | 69 | III | TRS | TP53 mutation | 1 | Negative | Low | Alive | 4.90 | | 45 | EC982T | M | 64 | IIB | TRS | TP53 mutation | 1 | Positive | Low | Alive | 4.90 | | 46 | EC983T | M | 44 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.95 | | 47 | EC191T | M | 59 | III | WES | TP53 mutation | 1 | Positive | Low | Dead | 4.18 | | 48 | EC984T | M | 63 | III | TRS | TP53 mutation | 1 | Positive | Low | Dead | 1.36 | | 49 | EC985T | M | 51 | III | TRS | TP53 mutation | 1 | Negative | Low | Alive | 5.30 | | 50 | EC986T | M | 72 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Dead | 3.24 | | 51 | EC987T | M | 67 | III | TRS | TP53 mutation | 1 | Positive | Low | Alive | 4.94 | | 52 | EC990T | M | 73 | III | TRS | TP53 mutation | 1 | Negative | Low | Dead | 1.64 | | 53 | EC991T | M | 67 | IVA | TRS | TP53 mutation | 1 | Positive | Low | Dead | 2.42 | | 54 | EC993T | M | 56 | III | TRS | TP53 wild-type | 0 | Negative | Low | Alive | 3.12 | | 55 | EC992T | M | 59 | IIA | TRS | TP53 mutation | 1 | Positive | Low | Alive | 4.96 | | 56 | EC994T | M | 47 | III | TRS | TP53 mutation | 1 | Positive | Low | Alive | 2.81 | | 57 | EC995T | M | 68 | IIA | TRS | TP53 wild-type | 0 | Negative | Low | Alive | 4.98 | | 58 | EC088T | M | 58 | III | WES | TP53 mutation | 1 | Negative | Low | Dead | 6.07 | | 59 | EC996T | F | 74 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 4.98 | | 60 | EC630T | F | 57 | IIA | TRS | TP53 mutation | 1 | Positive | High | Dead | 2.79 | | 61 | EC997T | F | 61 | IIA | TRS | TP53 mutation | 1 | Positive | Low | Alive | 4.98 | | 62 | EC629T | M | 67 | IIB | TRS | TP53 mutation | 1 | Positive | Low | Dead | 2.43 | | 63 | EC1006T | M | 58 | III | TRS | TP53 mutation | 2 | Positive | High | Alive | 5.04 | | 64 | EC885T | M | 65 | IIB | TRS | TP53 mutation | 2 | Positive | Low | Dead | 4.01 | | 65 | EC1005T | F | 73 | III | TRS | TP53 mutation | 1 | Positive | Low | Dead | 2.92 | | 66 | EC886T | M | 62 | IIB | TRS | TP53 wild-type | 0 | Positive | High | Dead | 1.56 | | 67 | G008_T | M | 71 | IIA | WES | TP53 mutation | 1 | Positive | High | Dead | 2.53 | | 68 | NR131225_2T | F | 70 | III | WGS | TP53 mutation | 1 | Negative | Low | Alive | 5.29 | | 69 | EC080T | M | 70 | I | WES | TP53 mutation | 1 | Positive | Low | Dead | 2.70 | | 70 | NR131225_3T | M | 55 | IIA | WGS | TP53 mutation | 1 | Positive | High | Alive | 5.32 | | 71 | NR131225_5T | F | 67 | IIA | WGS | TP53 mutation | 1 | Negative | Low | Dead | 0.93 | | 72 | NR131225_9T | M | 67 | IIA | WGS | TP53 mutation | 1 | Negative | Low | Alive | 5.67 | | 73 | NR131225_4T | M | 74 | IIA | WGS | TP53 mutation | 1 | Positive | Low | Dead | 3.61 | | 74 | NR131225_10T | M | 77 | III | WGS | TP53 wild-type | 0 | Negative | Low | Dead | 2.50 | | 75 | NR131225_1T | F | 57 | III | WGS | TP53 mutation | 1 | Positive | High | Dead | 3.70 | | 76 | NR131225_8T | M | 58 | III | WGS | TP53 wild-type | 0 | Positive | Low | Alive | 5.36 | | 77 | NR131225_6T | M | 60 | IIA | WGS | TP53 mutation | 1 | Positive | High | Dead | 2.83 | | 78 | NR131121_10T | M | 53 | IIA | WGS | TP53 mutation | 1 | Positive | High | Dead | 0.66 | | 79 | NR131121_9T | M | 66 | IIB | WGS | TP53 mutation | 1 | Positive | High | Dead | 1.00 | | 80 | EC076T | M | 60 | III | WES | TP53 wild-type | 0 | Positive | Low | Alive | 11.19 | | 81 | NR131121_8T | M | 60 | IIA | WGS | TP53 mutation | 1 | Positive | Low | Dead | 4.00 | | 82 | NR131121_7T | M | 59 | IIB | WGS | TP53 mutation | 1 | Positive | Low | Dead | 5.27 | | 83 | NR131121_6T | M | 69 | IIA | WGS | TP53 mutation | 1 | Positive | High | Dead | 1.01 | | 84 | NR131121_5T | F | 64 | III | WGS | TP53 mutation | 1 | Positive | Low | Alive | 4.80 | | 85 | NR131121_4T | M | 65 | III | WGS | TP53 mutation | 1 | Positive | High | Dead | 0.58 | | 86 | NR131121_3T | F | 72 | IIA | WGS | TP53 mutation | 1 | Positive | Low | Alive | 5.57 | | 87 | NR131121_2T | M | 61 | IIA | WGS | TP53 mutation | 2 | Positive | High | Dead | 4.49 | | 88 | NR131121_1T | M | 63 | IIA | WGS | TP53 mutation | 1 | Positive | High | Dead | 2.03 | | 89 | TW2352AF | M | 55 | IIA | WES | TP53 mutation | 1 | Positive | Low | Alive | 7.87 | | 90 | TW2351BF | M | 46 | IIA | WES | TP53 mutation | 1 | Positive | High | Alive | 8.28 | | 91 | EC062T | F | 59 | III | WES | TP53 mutation | 1 | Positive | Low | Dead | 6.49 | | 92 | EC129T | M | 54 | IIA | WES | TP53 mutation | 1 | Negative | Low | Alive | 10.30 | | 93 | EC127T | F | 72 | IIB | WES | TP53 mutation | 1 | Negative | Low | Dead | 8.45 | | 94 | MC16T | M | 62 | IIA | WES | TP53 mutation | 1 | Negative | Low | Dead | 7.80 | | 95 | MC17T | M | 50 | IIA | WES | TP53 mutation | 2 | Positive | Low | Dead | 6.87 | | 96 | MC13T | M | 54 | III | WES | TP53 mutation | 1 | Positive | High | Dead | 4.25 | | 97 | MC7T | M | 53 | III | WES | TP53 mutation | 2 | Positive | High | Dead | 0.75 | | 98 | TW258AF | M | 40 | III | WES | TP53 mutation | 1 | Positive | High | Dead | 0.60 | | 99 | FE0008T | M | 64 | III | TRS | TP53 mutation | 1 | Positive | High | Dead | 0.83 | | 100 | EC123T | M | 56 | IIA | WES | TP53 mutation | 1 | Positive | Low | Dead | 4.06 | | 101 | G556T | M | 64 | III | TRS | TP53 mutation | 1 | Positive | Low | Alive | 2.65 | | 102 | G406T | M | 69 | III | TRS | TP53 mutation | 1 | Positive | High | Dead | 0.46 | | 103 | FG0067T | M | 68 | III | TRS | TP53 mutation | 2 | Positive | High | Alive | 1.10 | | 104 | EC745T | M | 64 | IIA | TRS | TP53 wild-type | 0 | Negative | Low | Alive | 2.95 | | 105 | G414T | M | 57 | III | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.11 | | 106 | EC727T | M | 70 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 3.14 | | 107 | EC720T | F | 74 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Dead | 1.16 | | 108 | EC718T | M | 64 | III | TRS | TP53 wild-type | 0 | Negative | Low | Dead | 1.66 | | 109 | EC721T | M | 56 | III | TRS | TP53 mutation | 1 | Positive | High | Dead | 0.48 | | 110 | EC943T | M | 65 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 3.79 | | 111 | EC121T | M | 59 | III | WES | TP53 mutation | 1 | Positive | High | Dead | 1.00 | | 112 | EC854T | F | 64 | IIA | TRS | TP53 mutation | 2 | Positive | High | Alive | 3.44 | | 113 | EC868T | F | 52 | III | TRS | TP53 mutation | 1 | Positive | Low | Alive | 3.44 | | 114 | EC686T | F | 59 | IIA | TRS | TP53 mutation | 2 | Positive | Low | Alive | 3.43 | | 115 | EC687T | F | 58 | IIA | TRS | TP53 wild-type | 0 | Positive | High | Dead | 0.92 | | 116 | EC685T | F | 78 | IIA | TRS | TP53 wild-type | 0 | Positive | Low | Alive | 3.47 | | 117 | EC884T | M | 63 | IIA | TRS | TP53 wild-type | 0 | Negative | Low | Alive | 3.45 | | 118 | EC883T | M | 62 | III | TRS | TP53 mutation | 2 | Positive | High | Alive | 3.49 | | 119 | EC881T | F | 62 | III | TRS | TP53 mutation | 1 | Positive | High | Dead | 1.24 | | 120 | EC877T | M | 68 | III | TRS | TP53 mutation | 1 | Positive | High | Alive | 3.51 | | 121 | EC880T | M | 68 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 3.47 | | 122 | EC122T | M | 52 | III | WES | TP53 mutation | 1 | Negative | Low | Alive | 11.47 | | 123 | EC876T | F | 47 | IIA | TRS | TP53 wild-type | 0 | Negative | Low | Alive | 3.51 | | 124 | EC871T | M | 78 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 3.51 | | 125 | EC874T | F | 64 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.53 | | 126 | EC855T | F | 67 | I | TRS | TP53 wild-type | 0 | Positive | High | Dead | 1.00 | | 127 | EC870T | F | 65 | III | TRS | TP53 wild-type | 0 | Positive | High | Alive | 3.91 | | 128 | EC872T | M | 64 | III | TRS | TP53 mutation | 1 | Positive | High | Dead | 0.89 | | 129 | EC875T | M | 68 | IIA | TRS | TP53 mutation | 1 | Positive | Low | Dead | 1.99 | | 130 | EC869T | M | 64 | I | TRS | TP53 mutation | 1 | Positive | High | Dead | 1.53 | | 131 | EC811T | F | 65 | IIA | TRS | TP53 wild-type | 0 | Positive | High | Dead | 2.22 | | 132 | G479T | M | 77 | IV | TRS | TP53 mutation | 1 | Positive | Low | Dead | 0.57 | | 133 | EC124T | M | 62 | III | WES | TP53 mutation | 1 | Positive | High | Dead | 2.07 | | 134 | EC814T | F | 61 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.58 | | 135 | EC813T | F | 60 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 3.58 | | 136 | EC816T | F | 66 | IIA | TRS | TP53 wild-type | 0 | Negative | Low | Dead | 3.21 | | 137 | EC812T | F | 72 | IIA | TRS | TP53 wild-type | 0 | Positive | High | Dead | 0.64 | | 138 | EC822T | M | 63 | IIA | TRS | TP53 mutation | 1 | Positive | Low | Alive | 3.95 | | 139 | EC818T | F | 53 | IIA | TRS | TP53 mutation | 2 | Positive | Low | Alive | 3.58 | | 140 | EC821T | F | 64 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 3.59 | | 141 | EC853T | F | 65 | IIA | TRS | TP53 wild-type | 0 | Positive | High | Alive | 2.64 | | 142 | EC832T | F | 72 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Dead | 0.25 | | 143 | EC851T | F | 67 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.64 | | 144 | EC120T | M | 65 | IIB | WES | TP53 mutation | 1 | Positive | High | Dead | 3.49 | | 145 | EC835T | M | 63 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Dead | 1.26 | | 146 | EC834T | F | 59 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.66 | | 147 | EC859T | M | 61 | III | TRS | TP53 mutation | 1 | Negative | Low | Dead | 1.02 | | 148 | EC850T | M | 72 | IIA | TRS | TP53 wild-type | 0 | Positive | Low | Alive | 3.69 | | 149 | EC838T | M | 58 | IIB | TRS | TP53 mutation | 1 | Positive | High | Alive | 2.67 | | 150 | EC849T | M | 64 | IIA | TRS | TP53 mutation | 1 | Positive | High | Dead | 1.26 | | 151 | EC848T | M | 53 | III | TRS | TP53 mutation | 1 | Positive | High | Alive | 3.73 | | 152 | EC847T | F | 65 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.72 | | 153 | EC845T | M | 57 | I | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.75 | | 154 | EC932T | F | 60 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Dead | 2.10 | | 155 | EC116T | F | 58 | IIA | WES | TP53 mutation | 1 | Positive | High | Alive | 11.53 | | 156 | EC934T | M | 70 | IIA | TRS | TP53 wild-type | 0 | Negative | Low | Dead | 1.44 | | 157 | EC935T | F | 64 | I | TRS | TP53 wild-type | 0 | Negative | Low | Alive | 3.76 | | 158 | EC933T | F | 66 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Dead | 3.20 | | 159 | EC941T | M | 62 | III | TRS | TP53 mutation | 1 | Negative | Low | Dead | 2.57 | | 160 | EC942T | F | 73 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.78 | | 161 | EC945T | M | 66 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 3.80 | | 162 | EC944T | F | 65 | IIB | TRS | TP53 mutation | 1 | Positive | High | Dead | 1.31 | | 163 | EC936T | F | 58 | IIA | TRS | TP53 wild-type | 0 | Positive | High | Alive | 3.79 | | 164 | EC937T | F | 60 | IIB | TRS | TP53 wild-type | 0 | Positive | High | Alive | 3.79 | | 165 | EC948T | F | 60 | IIB | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.81 | | 166 | EC117T | M | 50 | III | WES | TP53 mutation | 3 | Positive | High | Dead | 1.03 | | 167 | EC146T | F | 51 | III | WES | TP53 mutation | 1 | Positive | Low | Dead | 3.25 | | 168 | EC940T | F | 69 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Dead | 3.09 | | 169 | EC938T | F | 63 | IIA | TRS | TP53 wild-type | 0 | Positive | Low | Dead | 1.08 | | 170 | EC939T | F | 52 | IIA | TRS | TP53 wild-type | 0 | Positive | High | Dead | 0.92 | | 171 | EC951T | F | 63 | IIA | TRS | TP53 mutation | 2 | Positive | High | Alive | 3.85 | | 172 | EC952T | F | 61 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.85 | | 173 | EC963T | F | 56 | IIA | TRS | TP53 mutation | 2 | Negative | Low | Alive | 3.86 | | 174 | EC958T | F | 71 | III | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.86 | | 175 | EC959T | F | 57 | III | TRS | TP53 wild-type | 0 | Negative | Low | Dead | 1.32 | | 176 | EC961T | F | 48 | IIA | TRS | TP53 mutation | 2 | Positive | High | Alive | 3.88 | | 177 | EC962T | M | 52 | IIA | TRS | TP53 mutation | 1 | Positive | Low | Alive | 4.24 | | 178 | EC118T | F | 65 | IIB | WES | TP53 mutation | 1 | Negative | Low | Dead | 3.05 | | 179 | EC956T | M | 55 | IIA | TRS | TP53 wild-type | 0 | Positive | Low | Alive | 3.91 | | 180 | EC960T | M | 51 | III | TRS | TP53 mutation | 2 | Positive | High | Dead | 1.98 | | 181 | EC954T | F | 69 | IIA | TRS | TP53 wild-type | 0 | Positive | Low | Alive | 3.91 | | 182 | EC955T | F | 52 | IIB | TRS | TP53 mutation | 1 | Negative | Low | Dead | 1.20 | | 183 | EC953T | M | 61 | IIA | TRS | TP53 wild-type | 0 | Positive | High | Dead | 1.27 | | 184 | EC802T | F | 63 | III | TRS | TP53 mutation | 1 | Negative | Low | Dead | 1.48 | | 185 | EC793T | M | 69 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.95 | | 186 | EC789T | M | 63 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.95 | | 187 | EC797T | M | 58 | III | TRS | TP53 mutation | 1 | Negative | Low | Alive | 4.33 | | 188 | EC798T | F | 59 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.96 | | 189 | EC115T | F | 69 | IIA | WES | TP53 mutation | 2 | Positive | High | Dead | 1.48 | | 190 | EC788T | F | 58 | IIA | TRS | TP53 wild-type | 0 | Positive | Low | Dead | 2.98 | | 191 | EC792T | M | 70 | IIA | TRS | TP53 mutation | 1 | Positive | Low | Dead | 3.21 | | 192 | EC791T | M | 61 | III | TRS | TP53 mutation | 3 | Positive | High | Dead | 1.25 | | 193 | EC790T | M | 79 | III | TRS | TP53 mutation | 1 | Negative | Low | Dead | 1.78 | | 194 | EC794T | M | 65 | III | TRS | TP53 mutation | 2 | Positive | High | Dead | 1.74 | | 195 | EC783T | M | 75 | III | TRS | TP53 mutation | 1 | Positive | High | Alive | 3.97 | | 196 | EC782T | M | 67 | IIA | TRS | TP53 wild-type | 0 | Positive | Low | Dead | 2.42 | | 197 | EC795T | F | 69 | IIA | TRS | TP53 mutation | 1 | Positive | High | Dead | 1.51 | | 198 | EC787T | M | 59 | III | TRS | TP53 mutation | 1 | Positive | High | Dead | 0.84 | | 199 | G521T | F | 65 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.63 | | 200 | EC113T | M | 64 | III | WES | TP53 mutation | 2 | Positive | Low | Alive | 11.54 | | 201 | EC780T | M | 49 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Dead | 1.96 | | 202 | EC786T | M | 66 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 4.05 | | 203 | EC781T | M | 72 | IIA | TRS | TP53 mutation | 1 | Positive | High | Dead | 1.33 | | 204 | EC785T | M | 47 | IIA | TRS | TP53 wild-type | 0 | Negative | Low | Alive | 4.06 | | 205 | EC779T | F | 52 | III | TRS | TP53 mutation | 1 | Positive | High | Alive | 4.42 | | 206 | EC766T | F | 62 | III | TRS | TP53 mutation | 1 | Positive | Low | Dead | 1.61 | | 207 | EC769T | F | 68 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 4.46 | | 208 | EC807T | F | 82 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 4.11 | | 209 | EC900T | F | 64 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 4.11 | | 210 | EC898T | M | 59 | III | TRS | TP53 mutation | 1 | Negative | Low | Alive | 4.13 | | 211 | EC015T | M | 63 | III | WES | TP53 wild-type | 0 | Positive | Low | Dead | 2.25 | | 212 | EC904T | F | 48 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 4.12 | | 213 | EC899T | M | 60 | IIB | TRS | TP53 wild-type | 0 | Positive | High | Alive | 4.12 | | 214 | EC908T | F | 56 | III | TRS | TP53 mutation | 1 | Positive | High | Dead | 1.88 | | 215 | EC907T | M | 60 | IIA | TRS | TP53 mutation | 1 | Positive | High | Dead | 15.80 | | 216 | EC901T | F | 76 | III | TRS | TP53 wild-type | 0 | Positive | Low | Dead | 3.13 | | 217 | EC902T | M | 48 | III | TRS | TP53 mutation | 1 | Positive | Low | Alive | 4.15 | | 218 | EC906T | M | 49 | IIA | TRS | TP53 mutation | 1 | Not detected | Not detected | Alive | 4.51 | | 219 | EC972T | M | 63 | IIA | TRS | TP53 wild-type | 0 | Positive | High | Dead | 0.98 | | 220 | EC910T | M | 65 | IIA | TRS | TP53 wild-type | 0 | Negative | Low | Alive | 4.14 | | 221 | G048_T | F | 64 | III | WES | TP53 wild-type | 0 | Positive | High | Dead | 0.70 | | 222 | TW094BF | M | 40 | III | WES | TP53 mutation | 2 | Positive | Low | Dead | 2.74 | | 223 | G042_T | M | 65 | III | WES | TP53 mutation | 1 | Negative | Low | Alive | 4.16 | | 224 | EC912T | F | 63 | IIA | TRS | TP53 wild-type | 0 | Positive | High | Dead | 2.14 | | 225 | EC911T | F | 52 | IIA | TRS | TP53 wild-type | 0 | Negative | Low | Dead | 0.46 | | 226 | EC909T | F | 56 | IIB | TRS | TP53 mutation | 1 | Negative | Low | Alive | 3.12 | | 227 | EC916T | F | 62 | IIA | TRS | TP53 mutation | 1 | Positive | Low | Alive | 4.18 | | 228 | EC915T | M | 67 | IIA | TRS | TP53 wild-type | 0 | Negative | Low | Alive | 4.19 | | 229 | EC913T | M | 70 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Dead | 3.05 | | 230 | EC917T | F | 62 | IIA | TRS | TP53 wild-type | 0 | Positive | High | Dead | 3.65 | | 231 | EC920T | F | 56 | III | TRS | TP53 mutation | 1 | Positive | High | Dead | 2.15 | | 232 | EC918T | M | 68 | III | TRS | TP53 mutation | 1 | Positive | High | Dead | 2.21 | | 233 | TW890BF | M | 65 | III | WES | TP53 mutation | 1 | Positive | Low | Dead | 2.35 | | 234 | G039_T | M | 64 | IIA | WES | TP53 wild-type | 0 | Negative | Low | Alive | 4.24 | | 235 | EC922T | M | 74 | IIB | TRS | TP53 wild-type | 0 | Positive | Low | Dead | 3.49 | | 236 | EC921T | F | 60 | IIB | TRS | TP53 mutation | 1 | Negative | Low | Dead | 2.00 | | 237 | EC923T | M | 68 | III | TRS | TP53 wild-type | 0 | Negative | Low | Dead | 2.90 | | 238 | EC924T | M | 57 | IIA | TRS | TP53 mutation | 1 | Positive | High | Dead | 3.30 | | 239 | EC683T | M | 46 | IIA | TRS | TP53 wild-type | 0 | Negative | Low | Alive | 4.42 | | 240 | EC684T | M | 56 | III | TRS | TP53 mutation | 1 | Negative | Low | Dead | 3.84 | | 241 | EC682T | M | 63 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 4.42 | | 242 | EC679T | M | 59 | III | TRS | TP53 wild-type | 0 | Negative | Low | Dead | 2.31 | | 243 | EC680T | F | 62 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 4.42 | | 244 | EC055T | M | 45 | III | WES | TP53 mutation | 1 | Positive | High | Dead | 0.88 | | 245 | EC681T | M | 70 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 4.44 | | 246 | EC678T | F | 48 | IIB | TRS | TP53 wild-type | 0 | Positive | Low | Dead | 1.37 | | 247 | EC676T | M | 57 | III | TRS | TP53 mutation | 1 | Negative | Low | Dead | 0.98 | | 248 | EC677T | M | 46 | III | TRS | TP53 mutation | 1 | Negative | Low | Alive | 4.44 | | 249 | EC672T | M | 57 | III | TRS | TP53 mutation | 1 | Negative | Low | Dead | 1.83 | | 250 | EC666T | F | 67 | IVA | TRS | TP53 mutation | 1 | Negative | Low | Dead | 1.54 | | 251 | EC660T | F | 66 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 4.50 | | 252 | EC658T | M | 59 | I | TRS | TP53 wild-type | 0 | Positive | High | Alive | 4.52 | | 253 | EC659T | F | 63 | III | TRS | TP53 mutation | 1 | Positive | High | Alive | 4.87 | | 254 | EC1002T | F | 62 | III | TRS | TP53 mutation | 1 | Positive | High | Alive | 4.65 | | 255 | EC039T | M | 74 | IIA | WES | TP53 wild-type | 0 | Negative | Low | Dead | 0.35 | | 256 | EC656T | F | 72 | IIA | TRS | TP53 wild-type | 0 | Negative | Low | Alive | 4.51 | | 257 | EC654T | F | 61 | III | TRS | TP53 wild-type | 0 | Positive | High | Dead | 0.96 | | 258 | EC651T | M | 51 | IIB | TRS | TP53 mutation | 1 | Positive | High | Alive | 4.53 | | 259 | EC645T | F | 57 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 4.55 | | 260 | EC928T | F | 61 | IIB | TRS | TP53 mutation | 2 | Positive | Low | Alive | 4.58 | | 261 | EC926T | M | 73 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 4.96 | | 262 | EC929T | F | 64 | I | TRS | TP53 mutation | 2 | Positive | High | Dead | 1.54 | | 263 | EC927T | M | 60 | IIB | TRS | TP53 mutation | 1 | Negative | Low | Dead | 1.99 | | 264 | EC1003T | M | 64 | III | TRS | TP53 wild-type | 0 | Positive | High | Dead | 1.78 | | 265 | EC038T | M | 68 | IIA | WES | TP53 mutation | 1 | Negative | Low | Dead | 1.47 | | 266 | EC930T | F | 58 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 4.91 | | 267 | EC931T | F | 57 | IIA | TRS | TP53 wild-type | 0 | Negative | Low | Alive | 4.63 | | 268 | EC1000T | M | 67 | IIA | TRS | TP53 mutation | 2 | Positive | Low | Alive | 4.64 | | 269 | EC999T | F | 75 | IIB | TRS | TP53 mutation | 1 | Positive | Low | Alive | 4.64 | | 270 | EC1001T | F | 68 | III | TRS | TP53 mutation | 2 | Positive | High | Dead | 1.92 | | 271 | G017_T | F | 67 | III | WES | TP53 mutation | 1 | Negative | Low | Alive | 4.70 | | 272 | EC894T | M | 66 | IIA | TRS | TP53 mutation | 1 | Positive | High | Alive | 4.68 | | 273 | EC887T | M | 77 | IIA | TRS | TP53 wild-type | 0 | Negative | Low | Alive | 4.68 | | 274 | EC895T | M | 73 | III | TRS | TP53 mutation | 1 | Positive | High | Dead | 2.11 | | 275 | EC890T | F | 64 | IIA | TRS | TP53 mutation | 1 | Negative | Low | Alive | 4.69 | | 276 | EC036T | M | 49 | I | WES | TP53 wild-type | 0 | Positive | High | Alive | 7.88 | | 277 | EC027T | M | 47 | IIA | WES | TP53 mutation | 1 | Positive | Low | Alive | 11.89 | | 278 | TW258BF | M | 40 | IIA | WES | TP53 mutation | 1 | Not detected | Not detected | Dead | 1.39 | | 279 | EC114T | M | 64 | III | WES | TP53 mutation | 1 | Not detected | Not detected | Alive | 10.78 | | 280 | EC099T | M | 58 | IIA | WES | TP53 mutation | 1 | Not detected | Not detected | Dead | 1.76 | | 281 | TW1375BF | M | 55 | I | WES | TP53 mutation | 1 | Not detected | Not detected | Alive | 9.72 | | 282 | EC067T | M | 50 | IVB | WES | TP53 wild-type | 0 | Not detected | Not detected | Dead | 1.98 | | 283 | EC107T | M | 56 | III | WES | TP53 mutation | 1 | Not detected | Not detected | Dead | 3.06 | | 284 | MC23T | F | 59 | III | WES | TP53 wild-type | 0 | Not detected | Not detected | Dead | 0.06 | | 285 | EC188T | M | 64 | IIA | WES | TP53 mutation | 1 | Not detected | Not detected | Dead | 1.93 | | 286 | MC27T | M | 56 | IIB | WES | TP53 wild-type | 0 | Not detected | Not detected | Dead | 1.99 | | 287 | EC101T | M | 73 | IIA | WES | TP53 wild-type | 0 | Not detected | Not detected | Dead | 2.51 | | 288 | EC081T | F | 68 | IIB | WES | TP53 mutation | 1 | Not detected | Not detected | Dead | 2.62 | | 289 | MC30T | F | 41 | IIB | WES | TP53 wild-type | 0 | Not detected | Not detected | Alive | 8.52 | | 290 | EC145T | M | 51 | III | WES | TP53 mutation | 1 | Not detected | Not detected | Alive | 2.88 | | 291 | EC131T | M | 49 | IVA | WES | TP53 mutation | 2 | Not detected | Not detected | Alive | 12.35 | | 292 | TW470BF | F | 49 | III | WES | TP53 mutation | 1 | Not detected | Not detected | Alive | 15.36 | | 293 | EC086T | M | 36 | IIA | WES | TP53 mutation | 1 | Not detected | Not detected | Alive | 11.00 | | 294 | EC013T | F | 69 | IIA | WES | TP53 wild-type | 0 | Not detected | Not detected | Dead | 2.92 | | 295 | EC126T | F | 63 | III | WES | TP53 mutation | 1 | Not detected | Not detected | Alive | 11.37 | | 296 | EC040T | M | 59 | III | WES | TP53 mutation | 2 | Not detected | Not detected | Alive | 8.24 | | 297 | TW1371BF | M | 44 | IIA | WES | TP53 mutation | 1 | Not detected | Not detected | Dead | 2.22 | | 298 | TW1371AF | M | 43 | IIB | WES | TP53 mutation | 1 | Not detected | Not detected | Dead | 0.92 | | 299 | MC34T | M | 51 | IIA | WES | TP53 mutation | 1 | Not detected | Not detected | Dead | 7.54 | | 300 | EC925T | M | 59 | IIB | TRS | TP53 wild-type | 0 | Not detected | Not detected | Dead | 1.77 | | 301 | CE2T | M | 54 | III | WES | TP53 mutation | 1 | Not detected | Not detected | Alive | 13.37 | | 302 | MC29T | M | 60 | IIB | WES | TP53 mutation | 1 | Not detected | Not detected | Dead | 4.26 | | 303 | EC034T | M | 62 | IIB | WES | TP53 mutation | 1 | Not detected | Not detected | Dead | 6.17 | | 304 | MC4T | M | 69 | IIA | WES | TP53 wild-type | 0 | Not detected | Not detected | Dead | 2.81 | | 305 | TW2309BF | F | 45 | IIA | WES | TP53 mutation | 1 | Not detected | Not detected | Alive | 11.74 | | 306 | EC128T | F | 51 | III | WES | TP53 mutation | 1 | Not detected | Not detected | Dead | 4.00 | | 307 | EC192T | M | 57 | III | WES | TP53 mutation | 1 | Not detected | Not detected | Dead | 2.78 | | 308 | EC061T | M | 76 | IIA | WES | TP53 wild-type | 0 | Not detected | Not detected | Dead | 5.83 | | 309 | TW002BF | M | 59 | I | WES | TP53 wild-type | 0 | Not detected | Not detected | Alive | 10.24 | | 310 | MC26T | M | 44 | III | WES | TP53 mutation | 1 | Not detected | Not detected | Dead | 1.66 | | 311 | EC060T | M | 50 | IIA | WES | TP53 mutation | 1 | Not detected | Not detected | Alive | 6.87 | | 312 | TW829AF | F | 60 | IIA | WES | TP53 mutation | 1 | Not detected | Not detected | Alive | 14.09 | | 313 | TW1099AF | M | 48 | IIA | WES | TP53 mutation | 2 | Not detected | Not detected | Alive | 11.02 | | 314 | EC094T | F | 58 | IIA | WES | TP53 mutation | 2 | Not detected | Not detected | Dead | 5.70 | | 315 | EC165T | M | 55 | III | WES | TP53 wild-type | 0 | Not detected | Not detected | Dead | 9.95 | | 316 | EC012T | F | 51 | IIA | WES | TP53 mutation | 1 | Not detected | Not detected | Dead | 1.36 |
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