Retinoblastoma-Binding Protein 5 Regulates H3K4 Methylation Modification to Inhibit the Proliferation of Melanoma Cells by Inactivating the Wnt/<i>β</i>-Catenin and Epithelial-Mesenchymal Transition Pathways

<div>RBBP5 inhibits the Wnt/<i>β</i>-catenin signalling pathway and EMT. (a–d) The effect of RBBP5 silencing on the Wnt/<i>β</i>-catenin signalling pathway and EMT marker expression was evaluated by western blotting in A375 and A2058 cells. (e–h) The effect of RBBP5 overexpression on the Wnt/<i>β</i>-catenin signalling pathway and EMT marker expression was evaluated by western blotting in A375 and A2058 cells. 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Journal of Oncology

fig6

Figure 6

Figure 6: Retinoblastoma-Binding Protein 5 Regulates H3K4 Methylation Modification to Inhibit the Proliferation of Melanoma Cells by Inactivating the Wnt/<i>β</i>-Catenin and Epithelial-Mesenchymal Transition Pathways 

Figure 6 | Retinoblastoma-Binding Protein 5 Regulates H3K4 Methylation Modification to Inhibit the Proliferation of Melanoma Cells by Inactivating the Wnt/β-Catenin and Epithelial-Mesenchymal Transition Pathways 