Research Article
The Role of Radiotherapy for Patients with Unresectable Locally Advanced Breast Cancer following Neoadjuvant Systemic Therapy
| | Progression at any site | | Parameters | Total (%) (n = 41) | DRT (%) (n = 31) | NART (%) (n = 10) | | LRP alone | 5 (12.2) | 5 (16.1) | 0 (0.0) | | DP alone | 15 (36.6) | 9 (29.0) | 6 (60.0) | | LRP + DP | 21 (51.2) | 17 (54.8) | 4 (40.0) |
| | Locoregional progression | | Parameters | Total (%) (n = 26) | DRT (%) (n = 22) | NART (%) (n = 4) | | Breast or CW alone | 18 (69.2) | 16 (72.7) | 2 (50.0) | | Regional nodes alone | 5 (19.2) | 3 (13.6) | 2 (50.0) | | Axilla alone | 1 | 1 | 0 | | IMN alone | 2 | 1 | 1 | | SCV/ICV alone | 1 | 1 | 0 | | Multiple regions | 1 | 0 | 1 | | CW + regional nodes | 3 (11.5) | 3 (13.6) | 0 (0.0) |
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DRT = definitive radiotherapy; NART = neoadjuvant radiotherapy; LRP = locoregional progression; DP = distant progression; CW = chest wall; SCV = supraclavicular; ICV = infraclavicular; IMN = internal mammary nodes.
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