The Role of Purine Metabolism-Related Genes PPAT and IMPDH1 in the Carcinogenesis of Intrahepatic Cholangiocarcinoma Based on Metabonomic and Bioinformatic Analyses

Figure 1

Serum metabolites. (a) PCA analysis. (b) PLS-DA analysis. (c) OPLS-DA analysis. (d) The top 25 metabolites were enriched. (e) Differential metabolite of volcano plot (|log2 (FC)| > 1). (f) The top 60 differential metabolites were screened.

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