Cell-Free DNA in Cerebrospinal Fluid Complements the Monitoring Value of Interleukin-10 in Newly Diagnosed Primary Central Nervous System Lymphoma

Table 2

Mutations in BCR pathway members in baseline CSF cfDNA of PCNSL patients.

ID	COO subtype	Best response	MYD88	CD79B	CARD11	BTK	TNFAIP3
P1	N/A	CR	WT	WT	WT	WT	WT
P3	GCB	PR	L265P	E192A/Y196S	WT	WT	WT
P4	Non-GCB	PR	WT	WT	WT	WT	WT
P5	GCB	PR	L265P	WT	WT	WT	WT
P6	GCB	PR	L265P	WT	WT	WT	WT
P8	GCB	PR	P258L	WT	WT	Splice	A501Rfs23
P10	N/A	CR	WT	WT	WT	WT	WT

COO: cell of origin, GCB: germinal center B cell, non-GCB: nongerminal center B cell, N/A: not available, and WT: wild-type.